ALDH18A1 FISH Probe
The ALDH18A1 FISH probe is designed to hybridize to the ALDH18A1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDH18A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALDH18A1-20-RE | 20 (40 μL) | 200 μL |  |
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| ALDH18A1-20-GO | 20 (40 μL) | 200 μL |  |
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| ALDH18A1-20-GR | 20 (40 μL) | 200 μL |  |
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| ALDH18A1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALDH18A1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALDH18A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ALDH18A1
Gene Name: Aldehyde Dehydrogenase 18 Family Member A1
Chromosome: CHR10: 97365685-97416567
Locus: 10q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALDH18A1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALDH18A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping