ALASH FISH Probe
The ALASH FISH probe is designed to hybridize to the ALASH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALAS1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALAS1-20-RE | 20 (40 μL) | 200 μL |  |
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| ALAS1-20-GO | 20 (40 μL) | 200 μL |  |
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| ALAS1-20-GR | 20 (40 μL) | 200 μL |  |
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| ALAS1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALAS1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALAS1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: ALAS1
Gene Name: 5'-aminolevulinate Synthase 1
Chromosome: CHR3: 52232115-52248343
Locus: 3p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ALASH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALAS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping