AGO1-PC FISH Probe
The AGO1-PC FISH probe is designed to hybridize to the AGO1-PC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
AGO1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
AGO1-20-RE | 20 (40 μL) | 200 μL | ||
AGO1-20-GO | 20 (40 μL) | 200 μL | ||
AGO1-20-GR | 20 (40 μL) | 200 μL | ||
AGO1-20-AQ | 20 (40 μL) | 200 μL | ||
AGO1-20-DIG | 20 (40 μL) | 200 μL | ||
AGO1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: AGO1
Gene Name: Argonaute 1, RISC Catalytic Component
Chromosome: CHR1: 35869807-35929609
Locus: 1p34.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AGO1-PC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AGO1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping