ABI2 FISH Probe
The ABI2 FISH probe is designed to hybridize to the ABI2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABI1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ABI1-20-RE | 20 (40 μL) | 200 μL |  |
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| ABI1-20-GO | 20 (40 μL) | 200 μL |  |
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| ABI1-20-GR | 20 (40 μL) | 200 μL |  |
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| ABI1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ABI1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ABI1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: ABI1
Gene Name: Abl Interactor 1
Chromosome: CHR10: 27035524-27150016
Locus: 10p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ABI2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ABI1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping