A2AAR FISH Probe
The A2AAR FISH probe is designed to hybridize to the A2AAR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ADORA2A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ADORA2A-20-RE | 20 (40 μL) | 200 μL |  |
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| ADORA2A-20-GO | 20 (40 μL) | 200 μL |  |
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| ADORA2A-20-GR | 20 (40 μL) | 200 μL |  |
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| ADORA2A-20-AQ | 20 (40 μL) | 200 μL |  |
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| ADORA2A-20-DIG | 20 (40 μL) | 200 μL |  |
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| ADORA2A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
Gene Details
Gene Symbol: ADORA2A
Gene Name: Adenosine A2a Receptor
Chromosome: CHR22: 24823529-24838325
Locus: 22q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: A2AAR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ADORA2A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping