5-HT1C FISH Probe
The 5-HT1C FISH probe is designed to hybridize to the 5-HT1C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HTR2C-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HTR2C-20-RE | 20 (40 μL) | 200 μL |  |
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| HTR2C-20-GO | 20 (40 μL) | 200 μL |  |
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| HTR2C-20-GR | 20 (40 μL) | 200 μL |  |
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| HTR2C-20-AQ | 20 (40 μL) | 200 μL |  |
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| HTR2C-20-DIG | 20 (40 μL) | 200 μL |  |
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| HTR2C-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: HTR2C
Gene Name: 5-hydroxytryptamine Receptor 2C
Chromosome: CHRX: 113818550-114144624
Locus: Xq23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 5-HT1C FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HTR2C-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping