5'OY11.1 FISH Probe
The 5'OY11.1 FISH probe is designed to hybridize to the 5'OY11.1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZNF280B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-RE | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-GO | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-GR | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-AQ | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-DIG | 20 (40 μL) | 200 μL |  |
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| ZNF280B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: ZNF280B
Gene Name: Zinc Finger Protein 280B
Chromosome: CHR22: 22838771-22863505
Locus: 22q11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 5'OY11.1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ZNF280B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping