4-1BBLRR FISH Probe
The 4-1BBLRR FISH probe is designed to hybridize to the 4-1BBLRR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LRR1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LRR1-20-RE | 20 (40 μL) | 200 μL |  |
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| LRR1-20-GO | 20 (40 μL) | 200 μL |  |
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| LRR1-20-GR | 20 (40 μL) | 200 μL |  |
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| LRR1-20-AQ | 20 (40 μL) | 200 μL |  |
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| LRR1-20-DIG | 20 (40 μL) | 200 μL |  |
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| LRR1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: LRR1
Gene Name: Leucine Rich Repeat Protein 1
Chromosome: CHR14: 50065414-50081390
Locus: 14q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: 4-1BBLRR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LRR1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping