3-OST-3B FISH Probe
The 3-OST-3B FISH probe is designed to hybridize to the 3-OST-3B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HS3ST3B1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HS3ST3B1-20-RE | 20 (40 μL) | 200 μL |  |
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| HS3ST3B1-20-GO | 20 (40 μL) | 200 μL |  |
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| HS3ST3B1-20-GR | 20 (40 μL) | 200 μL |  |
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| HS3ST3B1-20-AQ | 20 (40 μL) | 200 μL |  |
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| HS3ST3B1-20-DIG | 20 (40 μL) | 200 μL |  |
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| HS3ST3B1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a type II integral membrane protein that belongs to the 3-O-sulfotransferases family. These proteins catalyze the addition of sulfate groups at the 3-OH position of glucosamine in heparan sulfate. The substrate specificity of individual members of the family is based on prior modification of the heparan sulfate chain, thus allowing different members of the family to generate binding sites for different proteins on the same heparan sulfate chain. Following treatment with a histone deacetylase inhibitor, expression of this gene is activated in a pancreatic cell line. The increased expression results in promotion of the epithelial-mesenchymal transition. In addition, the modification catalyzed by this protein allows herpes simplex virus membrane fusion and penetration. A very closely related homolog with an almost identical sulfotransferase domain maps less than 1 Mb away. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: HS3ST3B1
Gene Name: Heparan Sulfate-glucosamine 3-sulfotransferase 3B1
Chromosome: CHR17: 14204505-14249492
Locus: 17p12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 3-OST-3B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HS3ST3B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping