16.3A5 FISH Probe
The 16.3A5 FISH probe is designed to hybridize to the 16.3A5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD59-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CD59-20-RE | 20 (40 μL) | 200 μL |  |
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| CD59-20-GO | 20 (40 μL) | 200 μL |  |
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| CD59-20-GR | 20 (40 μL) | 200 μL |  |
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| CD59-20-AQ | 20 (40 μL) | 200 μL |  |
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| CD59-20-DIG | 20 (40 μL) | 200 μL |  |
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| CD59-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CD59
Gene Name: CD59 Molecule (CD59 Blood Group)
Chromosome: CHR11: 33724555-33758025
Locus: 11p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 16.3A5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD59-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping