SLC9A8-TOM1L2 Fusion FISH Probe
The SLC9A8-TOM1L2 Fusion FISH Probe is used to confirm a fusion of the SLC9A8 and TOM1L2 genes. The fusion of the SLC9A8 and TOM1L2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC9A8-TOM1L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-RERE | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-REOR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-REGO | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-REGR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-OROR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GORE | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GROR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC9A8-TOM1L2-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC9A8 Gene Summary
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).[supplied by OMIM, Apr 2009]
Gene Name: Solute Carrier Family 9 Member A8
Chromosome: CHR20: 48429249 -48508772
Locus: 20q13.13
TOM1L2 Gene Summary
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Apr 2017]
Gene Name: Target Of Myb1 Like 2 Membrane Trafficking Protein
Chromosome: CHR17: 17746821 -17875784
Locus: 17p11.2
Gene Diseases
The SLC9A8 TOM1L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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