PTPRJ-C2CD2L Fusion FISH Probe
The PTPRJ-C2CD2L Fusion FISH Probe is used to confirm a fusion of the PTPRJ and C2CD2L genes. The fusion of the PTPRJ and C2CD2L genes has been associated with Acute Myeloid Leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRJ-C2CD2L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRJ-C2CD2L-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRJ Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type J
Chromosome: CHR11: 48002109 -48192394
Locus: 11p11.2
C2CD2L Gene Summary
The C2CD2 Like (C2CD2L) gene is located on chr11 :118978092-118987827 at 11q23.3.
Gene Name: C2CD2 Like
Chromosome: CHR11: 118978092 -118987827
Locus: 11q23.3
Gene Diseases
The PTPRJ C2CD2L Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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