NEK7-CRB1 Fusion FISH Probe
The NEK7-CRB1 Fusion FISH Probe is used to confirm a fusion of the NEK7 and CRB1 genes. The fusion of the NEK7 and CRB1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NEK7-CRB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-RERE | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-REOR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-REGO | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-REGR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-REAQ | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-ORRE | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-OROR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-ORGO | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GORE | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GOOR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GOGO | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GOGR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GRRE | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GROR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GRGO | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GRGR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-AQRE | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-AQOR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-AQGO | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-AQGR | 20 (40 μL) | 200 μL |
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| NEK7-CRB1-20-AQAQ | 20 (40 μL) | 200 μL |
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CRB1 Gene Summary
This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012]
Gene Name: Crumbs 1, Cell Polarity Complex Component
Chromosome: CHR1: 197237333 -197447585
Locus: 1q31.3
NEK7 Gene Summary
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]
Gene Name: NIMA Related Kinase 7
Chromosome: CHR1: 198126107 -198291548
Locus: 1q31.3
Gene Diseases
The NEK7 CRB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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