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MRPL50-C9ORF125 Fusion FISH Probe

The MRPL50-C9ORF125 Fusion FISH Probe is used to confirm a fusion of the MRPL50 and C9ORF125 genes. The fusion of the MRPL50 and C9ORF125 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MRPL50-C9ORF125-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-RERE 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-REOR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-REGO 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-REGR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-REAQ 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-ORRE 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-OROR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-ORGO 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-ORAQ 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GORE 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GOOR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GOGO 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GOGR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GOAQ 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GRRE 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GROR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GRGO 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GRGR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-GRAQ 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-AQRE 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-AQOR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-AQGO 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-AQGR 20 (40 μL) 200 μL
MRPL50-C9ORF125-20-AQAQ 20 (40 μL) 200 μL

MRPL50 Gene Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008]

Gene Name: Mitochondrial Ribosomal Protein L50

Chromosome: CHR9: 104152248 -104160919

Locus: 9q31.1

Gene Diseases

The MRPL50 C9ORF125 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.