LMBR1-EPHA1 Fusion FISH Probe
The LMBR1-EPHA1 Fusion FISH Probe is used to confirm a fusion of the LMBR1 and EPHA1 genes. The fusion of the LMBR1 and EPHA1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LMBR1-EPHA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-RERE | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-REOR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-REGO | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-REGR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-REAQ | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-ORRE | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-OROR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-ORGO | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GORE | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GOOR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GOGO | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GOGR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GRRE | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GROR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GRGO | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GRGR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-AQRE | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-AQOR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-AQGO | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-AQGR | 20 (40 μL) | 200 μL |
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| LMBR1-EPHA1-20-AQAQ | 20 (40 μL) | 200 μL |
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EPHA1 Gene Summary
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008]
Gene Name: EPH Receptor A1
Chromosome: CHR7: 143088204 -143105985
Locus: 7q34-q35
LMBR1 Gene Summary
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]
Gene Name: Limb Development Membrane Protein 1
Chromosome: CHR7: 156473569 -156685902
Locus: 7q36.3
Gene Diseases
The LMBR1 EPHA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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