EXOC6B-PCCB Fusion FISH Probe
The EXOC6B-PCCB Fusion FISH Probe is used to confirm a fusion of the EXOC6B and PCCB genes. The fusion of the EXOC6B and PCCB genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EXOC6B-PCCB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-RERE | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-REOR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-REGO | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-REGR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-REAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-ORRE | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-OROR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-ORGO | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-ORAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GORE | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GOOR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GOGO | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GOGR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GOAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GRRE | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GROR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GRGO | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GRGR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-GRAQ | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-AQRE | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-AQOR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-AQGO | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-AQGR | 20 (40 μL) | 200 μL |
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| EXOC6B-PCCB-20-AQAQ | 20 (40 μL) | 200 μL |
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PCCB Gene Summary
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
Gene Name: Propionyl-CoA Carboxylase Beta Subunit
Chromosome: CHR3: 135969166 -136049013
Locus: 3q22.3
EXOC6B Gene Summary
This gene encodes a protein which is a part of the evolutionarily conserved exocyst, a multimeric protein complex necessary for exocytosis, which in turn, is crucial for cell growth, polarity and migration. Disruption of this gene may be associated with phenotypes exhibiting multiple symptoms including intellectual disability and developmental delay (DD). [provided by RefSeq, Jun 2016]
Gene Name: Exocyst Complex Component 6B
Chromosome: CHR2: 72406443 -73053177
Locus: 2p13.2
Gene Diseases
The EXOC6B PCCB Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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