EBF4-TMC2 Fusion FISH Probe
The EBF4-TMC2 Fusion FISH Probe is used to confirm a fusion of the EBF4 and TMC2 genes. The fusion of the EBF4 and TMC2 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EBF4-TMC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-RERE | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-REOR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-REGO | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-REGR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-REAQ | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-ORRE | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-OROR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-ORGO | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GORE | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GOOR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GOGO | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GOGR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GRRE | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GROR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GRGO | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GRGR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-AQRE | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-AQOR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-AQGO | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-AQGR | 20 (40 μL) | 200 μL |
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| EBF4-TMC2-20-AQAQ | 20 (40 μL) | 200 μL |
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EBF4 Gene Summary
EBF4 belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, members of which play important roles in neural development and B-cell maturation (Wang et al., 2002 [PubMed 12139918]).[supplied by OMIM, Mar 2008]
Gene Name: Early B-cell Factor 4
Chromosome: CHR20: 2673523 -2740754
Locus: 20p13
TMC2 Gene Summary
This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Aug 2015]
Gene Name: Transmembrane Channel Like 2
Chromosome: CHR20: 2517252 -2622430
Locus: 20p13
Gene Diseases
The EBF4 TMC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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